Company:  ELOXX PHARMACEUTICALS, IN ... (ELOX)
Form Type:  SC 13G/A
Filing Date:  2/11/2019 
CIK:  0001035354 
Address:  950 WINTER STREET 
City, State, Zip:  WALTHAM, Massachusetts 02451 
Telephone:  (858) 909-0749 
Fiscal Year:  06/30 
Last Trade
Last Trade: 
$12.73  
Change: 
0.28 (2.25%)  
Trade Time: 
11:45 AM EST  
Market Cap: 
$457.59M
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Description of Business
We are a clinical-stage biopharmaceutical company developing novel ribonucleic acid (RNA)-modulating drug candidates (designed to be eukaryotic ribosomal selective glycosides (ERSG)) that are formulated to treat rare and ultra-rare premature stop codon diseases. Premature stop codons are point mutations that disrupt the stability of the impacted messenger RNA (mRNA) and the protein synthesis from that mRNA. As a consequence, patients with premature stop codon diseases have reduced levels of, or no, protein from a gene whose product performs an essential function. This type of mutation accounts for some of the most severe phenotypes across genetic diseases. Nonsense mutations have been identified in over 1,800 rare and ultra-rare diseases. Read-through therapeutic development is focused on increasing mRNA stability and enabling functional protein synthesis.
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  FORM SC 13G/A